Risk Factors for Systemic Inflammatory Response Syndrome in Patients with Negative Preoperative Urine Culture after Percutaneous Nephrolithotomy

OBJECTIVE To explore the risk factors for systemic inflammatory response syndrome (SIRS) after percutaneous nephrolithotomy (PCNL) in patients with preoperative negative urine culture (UC). STUDY DESIGN Observational study. PLACE AND DURATION OF Department of Urology, Gazi Hospital, Samsun, Turkey, from January 2015 to 2020. METHODOLOGY Two hundred and twenty-eight patients, who underwent conventional PCNL renal stones, were evaluated. The divided into non-SIRS (Group 1) SIRS 2) groups, effects variables investigated predict development SIRS. RESULTS Despite sterile UC, developed postoperatively 29 (12.7%) patients. univariate analysis revealed a statistically significant difference between groups serum C-reactive protein (CRP) (p 117.36 3.16 mg/L 471 mm2 = 0.023) hemoglobin drop >2.3 g/L <0.001) are independent post-operative PCNL. CONCLUSION PLR, CRP, stone size, can This finding may help classify before PCNL, especially those culture. Key Words: protein, Percutaneous nephrolithotomy, Platelet/lymphocyte ratio, Systemic syndrome.